High Intensity Laser Therapy in the treatment of gonarthrosis: the first clinical cases and the protocol for a multicentric, randomised, double-blind study
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چکیده
Cartilage possesses scarce reparative capacities and until several years ago spontaneous or therapeutic repair of an articular lesion was not considered possible. At the present time the most common cartilaginous pathology, Arthrosis (osteoarthritis) is the focus of great interest on a worldwide level and has become the “new frontier” not only for orthopaedics but also for rheumatology and rehabilitation, to which a great deal of energy and resources are dedicated. Arthrosis is certainly the disease with the greatest increase in the number of cases in the western world in consideration of the general aging of the population. The social and economic role of arthrosis is therefore potentially very high. Numerous drugs have been proposed for the therapy of arthrosis including: the new FANS (selective inhibitors of the COX 2), basic drugs: DMOADs (Disease Modifying Osteoarthritis Drugs) better known as chondroprotectors, theoretically capable of intervening in both the destructive and reparative process of the disease, which include galactosamineglucuronoglican sulphate, diacereine, jaluronic acid. The real effectiveness of the DMOADs still has to be demonstrated and the clinical impression is that these molecules represent the forerunners of a new generation of drugs. Orthopaedics have developed a series of reparative surgical interventions of great interest aimed principally at knee-cartilage reconstruction.
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